opendermProtocolRetinol · four-acid30 G
openderm.CERTIFICATE OF GUARANTEEFORMULATION N° 43 / 43Pigment ProtocolYELLOW PEELRetinol · Glycolic · LacticKojicGuaranteed by OpenDerm LLC to be compoundedunder GMP, to its stated strengths.MEDIUM · 30 GAUTHORISED · OPENDERM LLCOPENDERM · GUARANTEED FORMULATION · GMPod.EST. 2026

For Resistant melasma · Dermal pigment · Post-inflammatory pigment

Pigment Protocol · Yellow Peel

Retinol, Glycolic, Lactic, Kojic · 30 g · medium depth

The flagship melasma protocol — a retinoid-led, self-neutralising four-acid cream peel. Applied in clinic, worn 4–6 hours, removed at home. For pigment that has resisted everything else.

Active
Retinol · four-acid
pH
null MEASURED
Depth
Medium
Size
30 g
Dwell
To endpoint
Endpoint
Level I–II frosting
Course
2–4 sessions
Interval
4–6 weeks
Price, direct
₹9,995
One published price — the same for every clinic.
Pharmaceutical-grade · GMP-manufactured · professional-use only.

The formulation

What it is, in full.

Primary systemRetinol · four-acid
CompositionRetinol, Glycolic, Lactic, Kojic
Peel depthMedium
VehicleAqueous · ethanol
Volume30 g
GradePharmaceutical
ManufactureIndia · GMP
Shelf life24 months
Active blend

Retinol, Glycolic, Lactic, Kojic.

Suitability

Honest about where it fits — and where it doesn't.

Best for

  • Resistant melasma
  • Dermal pigment
  • Post-inflammatory pigment

Not suitable for

  • Active dermatitis, eczema or broken skin
  • Oral isotretinoin within the last 6 months
  • Pregnancy or breastfeeding (defer)
  • Known sensitivity to the acids listed
  • Recent waxing, laser or resurfacing

How it works

What it is, and how it works.

The flagship melasma protocol — a retinoid-led, self-neutralising four-acid cream peel. Applied in clinic, worn 4–6 hours, removed at home. For pigment that has resisted everything else.

It leads with Retinol · four-acid to drive retinol and four acids into resistant pigment over a timed, take-home mask. As a medium-depth peel, penetration is controlled by strength and dwell time, so the practitioner sets the intensity to the skin.

Clinical strengths, stated plainly. The actives and their strengths are printed on every label — so you know exactly what you're applying and why.

Protocol

5 steps. Written for the practitioner.

01

Prep

Cleanse and degrease. Apply prep solution to standardise the surface.

02

Apply

One to two even coats by brush or gauze. Avoid the orbital and lip margins.

03

Dwell

Leave on for the timed interval, watching erythema and any frosting.

04

Neutralise

Apply neutraliser until effervescence stops, then rinse thoroughly.

05

Aftercare

Soothing barrier cream and broad-spectrum SPF. Sun avoidance 5–7 days.

Documentation

The paperwork comes standard.

Considered with

The rest of the short list.

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